L -Cysteine
Names
IUPAC name
Cysteine
Other names
2-Amino-3-sulfhydrylpropanoic acid
Except where otherwise noted, data are given for materials in their
standard state (at 25
°C [77
°F], 100
kPa).
Y verify (what is Y N ?)
Infobox references
Skeletal formula of L-cysteine
Cysteine (abbreviated as Cys or C )[ 1] is an α-amino acid . It has the chemical formula HO2 CCH(NH2 )CH2 SH.
Cysteine is a semi-essential amino acid, which means that humans can make it.[ 2] The codons UGU and UGC code for cysteine. The thiol side chain in cysteine often does enzyme reactions as a nucleophile . The thiol oxidises to give the disulfide derivative cystine, which is important in many protein structures. When used as a food additive, cysteine has the E number E920 .
References
Encoded (proteinogenic) amino acids
General topics By properties
Aliphatic
Alanine
Branched-chain amino acids (Valine
Isoleucine
Leucine)
Methionine
Proline
Glycine
Aromatic Polar, uncharged Positive charge (pK a )
Histidine (≈6.1)
Lysine (≈10.8)
Arginine (≈12.5)
Pyrrolysine
Negative charge (pK a )
Amino acids types : Encoded (proteins)
Essential
Non-proteinogenic
Ketogenic
Glucogenic
Secondary amino
Imino acids
D-amino acids
Dehydroamino acids
K→acetyl-CoA
lysine→
Saccharopine
Allysine
α-Aminoadipic acid
2-Oxoadipic acid
Glutaryl-CoA
Glutaconyl-CoA
Crotonyl-CoA
β-Hydroxybutyryl-CoA
leucine→
β-Hydroxy β-methylbutyric acid
β-Hydroxy β-methylbutyryl-CoA
Isovaleryl-CoA
α-Ketoisocaproic acid
β-Ketoisocaproic acid
β-Ketoisocaproyl-CoA
β-Leucine
β-Methylcrotonyl-CoA
β-Methylglutaconyl-CoA
β-Hydroxy β-methylglutaryl-CoA
tryptophan →alanine →
N ′-Formylkynurenine
Kynurenine
Anthranilic acid
3-Hydroxykynurenine
3-Hydroxyanthranilic acid
2-Amino-3-carboxymuconic semialdehyde
2-Aminomuconic semialdehyde
2-Aminomuconic acid
Glutaryl-CoA
G
G→pyruvate → citrate
glycine→ serine→
glycine→creatine : Glycocyamine
Phosphocreatine
Creatinine
G→glutamate → α-ketoglutarate
histidine →
Urocanic acid
Imidazol-4-one-5-propionic acid
Formiminoglutamic acid
Glutamate-1-semialdehyde
proline→
1-Pyrroline-5-carboxylic acid
arginine→
Agmatine
Ornithine
Citrulline
Cadaverine
Putrescine
other
G→propionyl-CoA→ succinyl-CoA
valine→
α-Ketoisovaleric acid
Isobutyryl-CoA
Methacrylyl-CoA
3-Hydroxyisobutyryl-CoA
3-Hydroxyisobutyric acid
2-Methyl-3-oxopropanoic acid
isoleucine→
2,3-Dihydroxy-3-methylpentanoic acid
2-Methylbutyryl-CoA
Tiglyl-CoA
2-Methylacetoacetyl-CoA
methionine→
generation of homocysteine: S -Adenosyl methionine
S -Adenosyl-L -homocysteine
Homocysteine
conversion to cysteine: Cystathionine
α-Ketobutyric acid + Cysteine
threonine →propionyl-CoA→
G→fumarate
G→oxaloacetate
Other