Olfactory bulb

Image of mouse main olfactory bulb cell nuclei.
Scale top to bottom is about 2mm

The olfactory bulb is a part of the vertebrate forebrain. It works in olfaction, or the sense of smell.

The olfactory bulb has one source of sensory input (axons from olfactory receptor neurons, and one output (mitral cell axons). It is thought that it functions as a filter. However, the olfactory bulb also gets "top-down" information from brain areas like the amygdala, neocortex, hippocampus, locus coeruleus, and substantia nigra.[1][2]

Its range of functions probably include:

  • discriminating between odors
  • enhancing sensitivity of odor detection
  • filtering out background odors
  • permitting higher brain areas involved in arousal and attention to modify the detection or discrimination of odors.

References

  1. ↑ Scott, J. W.; Wellis, D. P.; Riggott, M. J.; Buonviso, N. (1993). "Functional organization of the main olfactory bulb". Microscopy Research and Technique. 24 (2): 142–156. doi:10.1002/jemt.1070240206. PMID 8457726.
  2. ↑ Linster, Christiane; Cleland, Thomas A. (2013). "Spatiotemporal Coding in the Olfactory System". 20 Years of Computational Neuroscience. pp. 229–242. doi:10.1007/978-1-4614-1424-7_11. ISBN 978-1-4614-1423-0.
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